Question: Is Epidiolex a controlled substance?

Answer: The Agricultural Improvement Act of 2018 (AIA) decontrolled hemp when it was signed into law on December 20, 2018. The AIA defines the term "hemp" to mean the plant Cannabis sativa L. and any part of that plant, including the seeds thereof and all derivatives, extracts, cannabinoids, isomers, acids, salts, and salts of isomers, whether growing or not, with a delta-9-tetrahydrocannabinol [THC] concentration of not more than 0.3 percent on a dry weight basis. 7 U.S.C. 1639o(1). The AIA also amended the Controlled Substances Act (CSA) by excluding "hemp" from the definition of marihuana under 21 U.S.C. 802(16) and excluding "tetrahydrocannabinols in hemp" from the listing of tetrahydrocannabinols under 21 U.S.C. 812(c). Pub. L. 115-334, 12619. EO-DEA105, October 21, 2020

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