Diversion Control Division, US Department of Justice, Drug Enforcement Administration




Renewal Applications


Starting June 2020, DEA will no longer send renewal notifications by US Postal Service. Instead, an electronic reminder to renew will be sent at 60, 45, 30, 15, and 5 days prior to the expiration date of the registration to the associated email address. All registrants should ensure that the email address listed on their registration is correct and active.

At this time, DEA will otherwise retain its current policy and procedures with respect to renewal and reinstatement of registration. This policy is as follows:

  • If a renewal application is submitted in a timely manner prior to expiration, the registrant may continue operations, authorized by the registration, beyond the expiration date until final action is taken on the application.
  • DEA allows the reinstatement of an expired registration for one calendar month after the expiration date. If the registration is not renewed within that calendar month, an application for a new DEA registration will be required.
  • Regardless of whether a registration is reinstated within the calendar month after expiration, federal law prohibits the handling of controlled substances or List 1 chemicals for any period of time under an expired registration.

DEA Form 224a – Retail Pharmacy, Hospital/Clinic, Practitioner, Teaching Institution, or Mid-Level Practitioner

DEA Form 225a – Manufacturer, Distributor, Researcher, Analytical Laboratory, Importer, Exporter

DEA Form 363a – Narcotic Treatment Programs

DEA Form 510a – Domestic Chemical

New Applications

DEA Form 224 – Retail Pharmacy, Hospital/Clinic, Practitioner, Teaching Institution, or Mid-Level Practitioner

DEA Form 225 – Manufacturer, Distributor, Researcher, Canine Handler, Analytical Laboratory, Importer, Exporter

DEA Form 363 – Narcotic Treatment Programs

DEA Form 510 – Domestic Chemical

Check the Status of My Application

Registration Tools

Chain Renewals

Request Copy of DEA Certificate

This form is not for change of address or matters pertaining to the renewal of your registration. For these matters call 1-800-882-9539; for change of address, use the Address Changes Form.

Request Copy of Last Application/Receipt

Online Pharmacy Modifications

  • Modify business activity from Retail Pharmacy to Retail Online Pharmacy
  • Modify business activity from Retail Online Pharmacy to Retail Pharmacy
  • Modify existing Retail Online Pharmacy Information

Official Order Forms

As of October 30, 2021, the Drug Enforcement Administration is implementing the mandatory use of a single sheet DEA 222 Order Form and the triplicate DEA Order Forms will no longer be available or utilized as stated in the Code of Federal Regulations §1305.20(a). If you are needing to relinquish unused triplicate DEA Order Forms, please send them to DEA Registration Section, 8701 Morrissette Drive, Springfield, Virginia 22152.

Large Volume Order Forms (DEA Form 222)

Make Changes to My DEA Registration

Name Changes | Schedule Changes | Drug Code Changes | Address Changes - Do not submit this until you have an approved state license for the new address. Please note that these changes will become effective immediately upon DEA approval.

Registration for Disposal of Controlled Substances

  • Modify eligible DEA registration to collect pharmaceutical controlled substances from ultimate users (e.g., patients)
  • Modify DEA registration to stop being a collector
  • Modify existing collector registration information

Search for Year Round Pharmaceutical Disposal Locations

Registrant Validation Toolset

  • Verification of DEA Registration - Conduct a verification of a DEA Registrant (DEA Registrant restricted access)
  • Registrant Datasets Access - Download the Registrant Datasets for in-house verifications (DEA Registrant restricted access)

Registration Resources

Registration Categories and Fees

Customer Service Plan for Registrants

Practitioner's State License Requirements

Mid-Level Practitioners (MLP) Authorization by State

Questions and Answers

Registrant Population (Active)

Summary | Active Registrants by State | Active Registrants by Business Activity | Active Chemical Handler Registrants | Qualifying Practitioners by State

State Licensing Boards

New DEA Number Series

DEA is announcing that, effective immediately, DOD personal service contractors will be issued a new DEA registration number that begins with the letter "G". This new first character will be in addition to the current first characters A, B, F of the DEA registration for practitioners. The G series DEA registration number will be listed in the database provided to NTIS and available on the DEA website validation query system.

Registrant type (first letter of DEA Number):

A/B/F/G – Hospital/Clinic/Practitioner/Teaching Institution/Pharmacy

M – Mid-Level Practitioner (NP/PA/OD/ET, etc.)

P/R – Manufacturer/Distributor/Researcher/Analytical Lab/Importer/Exporter/Reverse Distributor/Narcotic Treatment Program

Registration Support

Call DEA Registration Service Center at 1-800-882-9539 (8:30 am-5:50 pm ET).

Email: DEA.Registration.Help@dea.gov - Be sure to include your DEA Registration number in your email.

Contact Local Registration Specialist

CMEA (Combat Meth Epidemic Act)

CMEA Required Training & Self-Certification

Monthly Self Certification List (Electronically downloadable formatted list of person who have self-certified)

Quota Applications

Marihuana Growers Information

Notice of Registration

Emergency Disaster Relief
Search for Year Round Pharmaceutical Disposal Locations.
National Prescription Drug Take Back Day. Turn in your unused or expired medication for safe disposal here.
RX Abuse Online

Diversion Control Division  •  8701 Morrissette Drive  •  Springfield, VA 22152  •  1-800-882-9539

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